EECE 434X - Implemn of Human Org-on-a-Chip

Credits: 3

This course introduces fundamentals of human organ-on-a-chip systems which refer to biomedical MEMS (bioMEMS) devices containing miniaturized human organs for drug screening, disease modeling and regenerative medicine. Topics to be covered in this course will focus on applications of electrical engineering principles combined with human cell culture techniques for the design, fabrication and interrogation of organ chip models of brain, lung, intestine and eye. The aims of the course include to: (i) study microfabrication and MEMS technologies in the context of human organ-on-a-chip implement and innovations; (ii) provide general background for in vitro cell culture techniques; (iii) review electrical, optical, biological sensor techniques for the analysis of organ-on-a-chip systems; and (iv) study the exemplary applications of organ-on-a-chip technology in biomedical research and medicine. This course also provides broad discussion on recent and future trends in human organ-on-a-chip systems and bioMEMS technologies. Prerequisites: EECE 332 or permission from instructor.